About 1 result found for searched term "BT2 " (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29950 | BT2 | Bcl-2 |
| BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC). BT2 is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM. | ||
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